منابع مشابه
Factors in Resistance to Tuberculosis *
The investigations of Sabin and her co-workerse9 demonstrated that the tubercie phosphatide was the biologically most active fraction of the various split-products of the tubercle bacillus as separated by Anderson.2 It produced epithelioid cell response and tubercle formation. Sabin also observed that, after intraperitoneal injection, the rabbit monocytes phagocytized the phosphatide, but were ...
متن کاملEnzymes as Factors in Resistance to Tuberculosis
Jobling and Petersen10 presented evidence as long ago as 1914 that the lipoids of tubercle bacilli inhibit proteolytic enzymes. More recently, Peck"5 has shown that these lipoids also inhibit crystallized trypsin and that the higher the molecular weight of the lipoid the greater is its interference with the enzyme function. Further investigation involving fractions of tubercle bacilli and enzym...
متن کاملFactors affecting susceptibility and resistance to tuberculosis.
Background: Susceptibility to disease after infection by Mycobacterium tuberculosis is influenced by environmental and host genetic factors. Vitamin D metabolism leads to activation of macrophages and restricts the intracellular growth of M tuberculosis. This effect may be influenced by polymorphisms at three sites in the vitamin D receptor (VDR) gene. We investigated the interaction between se...
متن کاملA STUDY OF MYCOBACTERIUM TUBERCULOSIS DRUG RESISTANCE IN PULMONARY TUBERCULOSIS
Tuberculosis remains a major public health problem in both developing and developed countries. Drug-resistant tuberculosis is an increasing health problem and serious challenge to tuberculosis (TB) control programs. Information about the susceptibility pattern of Mycobacterium tuberculosis isolates against anti-tuberculosis drugs is an important aspect to TB control. The objectives of the s...
متن کاملDrug resistance pattern and associated risk factors of tuberculosis patients in Iran\'s Central Province
Background: One of the fundamental issues of infectious disease treatment is drug resistance. The aim of the present study was to investigate the first-line anti-tuberculosis drug resistance rates and determine the risk factors related to multidrug resistant mycobacterium tuberculosis.Methods: From March 2011 to September 2012, mycobacterial strains were collected from one hundred fifteen diagn...
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ژورنال
عنوان ژورنال: Archives of Internal Medicine
سال: 1918
ISSN: 0003-9926
DOI: 10.1001/archinte.1918.00090070023002